| 2024 | |
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Rank M, Kather A, Wilke D, Steib-Bauert M, Kern W, Roeder I, De With K
Limitations of estimating antibiotic resistance using German hospital consumption data - A comprehensive computational analysis Preprint (2024), DOI Link |
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Baumgärtner JL, Stodtmeister R, Mauer R, Pillunat LE, Pillunat KR
The retinal venous pressure at different levels of airway pressure measured with a new method. Graefe's archive for clinical and experimental ophthalmology (2024), DOI Link |
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Bereuter JP, Geissler ME, Klimova A, Geissler R, Oswald C, El-Armouche A, El-Armouche K, Günther L, Deußen A
Do We Need More Structured MD Thesis Programs? A Propensity Score Matched Analysis of the Research Program at the Medical Faculty Dresden. Medical science educator 34 (2024) 1011-1021, DOI Link |
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Doenhardt M, Hufnagel M, Diffloth N, Hübner J, Mauer R, Schneider DT, Simon A, Tenenbaum T, Trotter A, Armann J, Berner R
Epidemiology of 7375 children and adolescents hospitalized with COVID-19 in Germany, reported via a prospective, nationwide surveillance study in 2020-2022. Scientific reports 14 (2024) 47, DOI Link |
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Eckstein V, Glaß K, Leßmann ME, Schaar J, Klimova A, Wimberger P, Goeckenjan M
Assisted reproduction after SARS-CoV-2-infection: results of a single-center cohort-study. Archives of gynecology and obstetrics 309 (2024) 305-313, DOI Link |
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Faria V, Höfer B, Klimova A, von der Hagen M, Berner R, Sabatowski R, Koch T, Hübler A, Richter M, Moulton EA, Holmes SA, Gossrau G
Sex and age-related patterns in pediatric primary headaches: observations from an outpatient headache clinic. Frontiers in neurology 15 (2024) 1441129, DOI Link |
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Kumar C, Kuhn M, Herrmann K, Leuchten N, Aringer M
Severe methotrexate toxicity in elderly patients under diuretics. RMD open 10 (2024), DOI Link |
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Pohl JE, Schwerk P, Mauer R, Hahn G, Beck R, Fitze G, Schultz J
Diagnosis of suspected pediatric distal forearm fractures with point-of-care-ultrasound (POCUS) by pediatric orthopedic surgeons after minimal training. BMC medical imaging 24 (2024) 255, DOI Link |
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Schmäche T, Fohgrub J, Klimova A, Laaber K, Drukewitz S, Merboth F, Hennig A, Seidlitz T, Herbst F, Baenke F, Ada AM, Groß T, Wenzel C, Ball CR, Praetorius C, Schmidt T, Ringelband-Schilling B, Koschny R, Stenzinger A, Roeder I, Jaeger D, Zeissig S, Welsch T, Aust D, Glimm H, Folprecht G, Weitz J, Haag GM, Stange DE
Stratifying esophago-gastric cancer treatment using a patient-derived organoid-based threshold. Molecular cancer 23 (2024) 10, DOI Link |
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Schwarz FM, Kuhlmann JD, Kämpfer J, Klimova A, Klotz DM, Freitag L, Herrmann P, Zinnow V, Smith J, Scheller T, Walther W, Wimberger P, Stein U
Induction of circulating ABCB1 transcripts under platinum-based chemotherapy indicates poor prognosis and a bone micrometastatic phenotype in ovarian cancer patients. Molecular cancer 23 (2024) 174, DOI Link |
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Stodtmeister R, Menzel A, Klimova A, Herber R, Pillunat KR, Pillunat LE
Measurement of the retinal venous pressure with a new instrument in patients with primary open angle glaucoma. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 262 (2024) 1633-1639, DOI Link |
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Stumpf J, Siepmann T, Schwöbel J, Karger C, Lindner TH, Faulhaber-Walter R, Langer T, Escher K, Anding-Rost K, Seidel H, Hüther J, Pistrosch F, Martin H, Schewe J, Stehr T, Meistring F, Paliege A, Schneider D, Steglich A, Gembardt F, Kessel F, Kröger H, Arndt P, Sradnick J, Frank K, Klimova A, Mauer R, Roeder I, Tonn T, Hugo C
Hybrid Immunity Protects against Antibody Fading after SARS-CoV-2mRNA Vaccination in Kidney Transplant Recipients, Dialysis Patients, and Medical Personnel: 9 Months Data from the Prospective, Observational Dia-Vacc Study. Vaccines 12 (2024), DOI Link |
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Winter S, Götze KS, Hecker JS, Metzeler KH, Guezguez B, Woods K, Medyouf H, Schäffer A, Schmitz M, Wehner R, Glauche I, Roeder I, Rauner M, Hofbauer LC, Platzbecker U
Clonal hematopoiesis and its impact on the aging osteo-hematopoietic niche. Leukemia (2024), DOI Link |
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Wittenstein J, Huhle R, Mutschke AK, Piorko S, Kramer T, Dorfinger L, Tempel F, Jäger M, Schweigert M, Mauer R, Koch T, Richter T, Scharffenberg M, Gama de Abreu M
Comparative effects of variable versus conventional volume-controlled one-lung ventilation on gas exchange and respiratory system mechanics in thoracic surgery patients: A randomized controlled clinical trial. Journal of clinical anesthesia 95 (2024) 111444, DOI Link |
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| 2023 | |
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Hoffmann K, Pelz A, Karg E, Gottschalk A, Zerjatke T, Schuster S, Böhme H, Glauche I, Roeder I
Data integration between clinical research and patient care: A framework for context-depending data sharing and in silico predictions. PLOS digital health 2 (2023) e0000140, DOI Link |
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Digomann D, Heiduk M, Reiche C, Glück J, Kahlert C, Mirtschink P, Klimova A, Bösch F, Tonn T, Gaedcke J, Ghadimi M, Weitz J, Seifert L, Seifert AM
Serum immune checkpoint profiling identifies soluble CD40 as a biomarker for pancreatic cancer. NPJ precision oncology 7 (2023) 104, DOI Link |
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Eckstein V, Glaß K, Leßmann ME, Schaar J, Klimova A, Wimberger P, Goeckenjan M
Assisted reproduction after SARS-CoV-2-infection: results of a single-center cohort-study. Archives of gynecology and obstetrics (2023), DOI Link |
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Faria V, Dulheuer J, Joshi A, Wahl H, Klimova A, Haehner A, Gossrau G
Impact of a 12-week olfactory training programme in women with migraine with aura: protocol for a double-blind, randomised, placebo-controlled trial. BMJ open 13 (2023) e071443, DOI Link |
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Gossrau G, Zaranek L, Klimova A, Sabatowski R, Koch T, Richter M, Haehner A
Olfactory training reduces pain sensitivity in children and adolescents with primary headaches. Frontiers in pain research (Lausanne, Switzerland) 4 (2023) 1091984, DOI Link |
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Hofmann A, Khorzom Y, Klimova A, Wolk S, Busch A, Sabarstinski P, Müglich M, Egorov D, Kopaliani I, Poitz DM, Kapalla M, Hamann B, Frank F, Jänichen C, Brunssen C, Morawietz H, Reeps C
Associations of Tissue and Soluble LOX-1 with Human Abdominal Aortic Aneurysm. Journal of the American Heart Association 12 (2023) e027537, DOI Link |
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Kresse-Walczak K, Meissner H, Mauer R, Trips E, Boening K
Evaluation of a protocol to assess a novel artificial biofilm equivalent for dentures-A prospective clinical pilot study. Gerodontology (2023), DOI Link |
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Lampe L, Huppertz HJ, Anderl-Straub S, Albrecht F, Ballarini T, Bisenius S, Mueller K, Niehaus S, Fassbender K, Fliessbach K, Jahn H, Kornhuber J, Lauer M, Prudlo J, Schneider A, Synofzik M, Kassubek J, Danek A, Villringer A, Diehl-Schmid J, Otto M, Schroeter ML
Multiclass prediction of different dementia syndromes based on multi-centric volumetric MRI imaging. NeuroImage. Clinical 37 (2023) 103320, DOI Link |
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Mainka A, Platzek I, Klimova A, Mattheus W, Fleischer M, Mürbe D
Relationship between epilarynx tube shape and the radiated sound pressure level during phonation is gender specific. Logopedics, phoniatrics, vocology 48 (2023) 44-56, DOI Link |
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Schoffer O, Schriefer D, Werblow A, Gottschalk A, Peschel P, Liang LA, Karmann A, Klug SJ
Modelling the effect of demographic change and healthcare infrastructure on the patient structure in German hospitals - a longitudinal national study based on official hospital statistics. BMC health services research 23 (2023) 1081, DOI Link |
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Stumpf J, Anders L, Siepmann T, Schwöbel J, Karger C, Lindner T, Faulhaber-Walter R, Langer T, Escher K, Anding-Rost K, Seidel H, Hüther J, Pistrosch F, Martin H, Schewe J, Stehr T, Meistring F, Paliege A, Schneider D, Bast I, Steglich A, Gembardt F, Kessel F, Kröger H, Arndt P, Sradnick J, Frank K, Skrzypczyk S, Anft M, Klimova A, Mauer R, Roeder I, Tonn T, Babel N, Hugo C
9-Month observational Dia-Vacc study of vaccine type influence on SARS-CoV-2 immunity in dialysis and kidney transplant patients. Vaccine (2023), DOI Link |
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Volz C, Zerjatke T, Gottschalk A, Semper S, Suttorp M, Glauche I, Krumbholz M, Metzler M
Continuous therapy response references for BCR::ABL1 monitoring in pediatric chronic myeloid leukemia. Scientific reports 13 (2023) 18199, DOI Link |
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White S, Mauer R, Lange C, Klimecki O, Huijbers W, Wirth M
The effect of plasma cortisol on hippocampal atrophy and clinical progression in mild cognitive impairment. Alzheimer's & dementia (Amsterdam, Netherlands) 15 (2023) e12463, DOI Link |
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Zaranek L, Sobe H, Richter M, Hübler A, Berner R, von der Hagen M, Koch T, Sabatowski R, Klimova A, Goßrau G
[Gender-specific results of the Dresden children and adolescents headache program DreKiP]. Schmerz (Berlin, Germany) (2023), DOI Link |
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| 2022 | |
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Karg E, Baldow C, Zerjatke T, Clark RE, Roeder I, Fassoni AC, Glauche I
Modelling of immune response in chronic myeloid leukemia patients suggests potential for treatment reduction prior to cessation. Frontiers in oncology 12 (2022) 1028871, DOI Link |
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Klimova A, Rudas T
Testing the fit of relational models Communications in Statistics - Theory and Methods 51 (2022) 8264-8282, DOI Link |
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Schwarz A, Roeder I, Seifert M
Comparative Gene Expression Analysis Reveals Similarities and Differences of Chronic Myeloid Leukemia Phases. Cancers 14 (2022), DOI Link |
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Adler SO, Spiesser TW, Uschner F, Münzner U, Hahn J, Krantz M, Klipp E
A yeast cell cycle model integrating stress, signaling, and physiology. FEMS yeast research (2022), DOI Link |
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Gossrau G, Frost M, Klimova A, Koch T, Sabatowski R, Mignot C, Haehner A
Interictal osmophobia is associated with longer migraine disease duration. The journal of headache and pain 23 (2022) 81, DOI Link |
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Hennig A, Baenke F, Klimova A, Drukewitz S, Jahnke B, Brückmann S, Secci R, Winter C, Schmäche T, Seidlitz T, Bereuter JP, Polster H, Eckhardt L, Schneider SA, Brückner S, Schmelz R, Babatz J, Kahlert C, Distler M, Hampe J, Reichert M, Zeißig S, Folprecht G, Weitz J, Aust D, Welsch T, Stange DE
Detecting drug resistance in pancreatic cancer organoids guides optimized chemotherapy treatment. The Journal of pathology 257 (2022) 607-619, DOI Link |
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Hofmann A, Hamann B, Klimova A, Müglich M, Wolk S, Busch A, Frank F, Sabarstinski P, Kapalla M, Nees JA, Brunssen C, Poitz DM, Morawietz H, Reeps C
Pharmacotherapies and Aortic Heme Oxygenase-1 Expression in Patients with Abdominal Aortic Aneurysm. Antioxidants (Basel, Switzerland) 11 (2022), DOI Link |
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Muallah D, Matschke J, Muallah S, Klimova A, Kroschwald LM, Schröder TA, Lauer G, Haim D
Socioeconomic disparities between oral cavity cancer patients in Germany. Frontiers in public health 10 (2022) 831479, DOI Link |
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Nickl R, Vicent O, Müller T, Osmers A, Schubert K, Koch T, Richter T
Impact of self-coiling catheters for continuous popliteal sciatic block on postoperative pain level and dislocation rate: a randomized controlled trial. BMC anesthesiology 22 (2022) 159, DOI Link |
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Pallesen LP, Winzer S, Hartmann C, Kuhn M, Gerber JC, Theilen H, Hädrich K, Siepmann T, Barlinn K, Rahmig J, Linn J, Barlinn J, Puetz V
Team Prenotification Reduces Procedure Times for Patients With Acute Ischemic Stroke Due to Large Vessel Occlusion Who Are Transferred for Endovascular Therapy. Frontiers in neurology 12 (2022) 787161, DOI Link |
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Pape K, Lößner AJ, William D, Czempiel T, Beyreuther E, Klimova A, Lehmann C, Schmäche T, Merker SR, Naumann M, Ada AM, Baenke F, Seidlitz T, Bütof R, Dietrich A, Krause M, Weitz J, Klink B, von Neubeck C, Stange DE
Sensitization of Patient-Derived Colorectal Cancer Organoids to Photon and Proton Radiation by Targeting DNA Damage Response Mechanisms. Cancers 14 (2022), DOI Link |
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Salmon M, White HE, Zizkova H, Gottschalk A, Motlova E, Cerveira N, Colomer D, Coriu D, Franke GN, Gottardi E, Izzo B, Jurcek T, Lion T, Schäfer V, Venturi C, Vigneri P, Zawada M, Zuna J, Hovorkova L, Koblihova J, Klamova H, Markova MS, Srbova D, Benesova A, Polivkova V, Zackova D, Mayer J, Roeder I, Glauche I, Ernst T, Hochhaus A, Polakova KM, Cross NCP
Impact of BCR::ABL1 transcript type on RT-qPCR amplification performance and molecular response to therapy. Leukemia 36 (2022) 1879-1886, DOI Link |
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Sedghi A, Heubner L, Klimova A, Tiebel O, Pietsch J, Mirus M, Barlinn K, Minx T, Beyer-Westendorf J, Puetz V, Spieth P, Siepmann T
Point-of-Care Assessment of Direct Oral Anticoagulation in Acute Ischemic Stroke: Protocol for a Prospective Observational Diagnostic Accuracy Study. Thrombosis and haemostasis 122 (2022) 1954-1962, DOI Link |
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Sidorova OA, Sayed S, Paszkowski-Rogacz M, Seifert M, Camgöz A, Roeder I, Bornhäuser M, Thiede C, Buchholz F
RNAi-Mediated Screen of Primary AML Cells Nominates MDM4 as a Therapeutic Target in NK-AML with DNMT3A Mutations. Cells 11 (2022), DOI Link |
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Sobe H, Richter M, Berner R, von der Hagen M, Hähner A, Röder I, Koch T, Sabatowski R, Klimova A, Gossrau G
Functional improvement in children and adolescents with primary headache after an interdisciplinary multimodal therapy program: the DreKiP study. The journal of headache and pain 23 (2022) 109, DOI Link |
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Stumpf J, Schwöbel J, Karger C, Schirutschke H, Mauer R, Klimova A, Tonn T, Hugo C
Anti-SARS-CoV-2 Revaccination Success in Kidney Transplant Recipients With No Initial Humoral Response Is Linked to Primary Vaccine Type. Frontiers in medicine 9 (2022) 910987, DOI Link |
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Stumpf J, Schwöbel J, Lindner T, Anders L, Siepmann T, Karger C, Hüther J, Martin H, Müller P, Faulhaber-Walter R, Langer T, Schirutschke H, Stehr T, Meistring F, Pietzonka A, Anding-Rost K, Escher K, Pistrosch F, Schewe J, Seidel H, Barnett K, Pluntke T, Cerny S, Paliege A, Bast I, Steglich A, Gembardt F, Kessel F, Kröger H, Arndt P, Sradnick J, Frank K, Klimova A, Mauer R, Grählert X, Tonn T, Hugo C
Risk of strong antibody decline in dialysis and transplant patients after SARS-CoV-2mRNA vaccination: Six months data from the observational Dia-Vacc study. The Lancet regional health. Europe 17 (2022) 100371, DOI Link |
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Stumpf J, Siepmann T, Schwöbel J, Glombig G, Paliege A, Steglich A, Gembardt F, Kessel F, Kröger H, Arndt P, Sradnick J, Frank K, Klimova A, Mauer R, Tonn T, Hugo C
MMF/MPA Is the Main Mediator of a Delayed Humoral Response With Reduced Antibody Decline in Kidney Transplant Recipients After SARS-CoV-2 mRNA Vaccination. Frontiers in medicine 9 (2022) 928542, DOI Link |
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Zhang K, Troeger W, Kuhn M, Wiedemann S, Ibrahim K, Pfluecke C, Sveric KM, Winzer R, Fedders D, Ruf TF, Strasser RH, Linke A, Quick S, Heidrich FM
Evaluation of systemic inflammation in response to remote ischemic preconditioning in patients undergoing transcatheter aortic valve replacement (TAVR). Reviews in cardiovascular medicine 23 (2022) 20, DOI Link |
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| 2021 | |
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Hoffmann H, Baldow C, Zerjatke T, Gottschalk A, Wagner S, Karg E, Niehaus S, Roeder I, Glauche I, Scherf N
How to predict relapse in leukemia using time series data: A comparative in silico study. PloS one 16 (2021) e0256585, DOI Link |
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Roeder I, Glauche I
Overlooking the obvious? On the potential of treatment alterations to predict patient-specific therapy response. Experimental hematology 94 (2021) 26-30, DOI Link |
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Wagner S, Thierbach K, Zerjatke T, Glauche I, Roeder I, Scherf N
TraCurate: Efficiently curating cell tracks SoftwareX 13 (2021) 100656, DOI Link |
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Hattab G, Hatzipanayioti A, Klimova A, Pfeiffer M, Klausing P, Breucha M, Bechtolsheim FV, Helmert JR, Weitz J, Pannasch S, Speidel S
Investigating the utility of VR for spatial understanding in surgical planning: evaluation of head-mounted to desktop display. Scientific reports 11 (2021) 13440, DOI Link |
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Romero Starke K, Mauer R, Karskens E, Pretzsch A, Reissig D, Nienhaus A, Seidler AL, Seidler A
The Effect of Ambient Environmental Conditions on COVID-19 Mortality: A Systematic Review. International journal of environmental research and public health 18 (2021), DOI Link |
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Seifert L, Plesca I, Müller L, Sommer U, Heiduk M, von Renesse J, Digomann D, Glück J, Klimova A, Weitz J, Schmitz M, Seifert AM
LAG-3-Expressing Tumor-Infiltrating T Cells Are Associated with Reduced Disease-Free Survival in Pancreatic Cancer. Cancers 13 (2021), DOI Link |
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Stelzner S, Puffer E, Zimmer J, Bleyl D, Kittner T, Kuhn M, Jakob C, Witzigmann H, Mees ST
Significant decrease of the pathological stage I rectal carcinoma in the era of neoadjuvant therapy-A matter of concern. European journal of cancer (Oxford, England : 1990) 159 (2021) 275-282, DOI Link |
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Stumpf J, Klimova A, Mauer R, Steglich A, Gembardt F, Martin H, Glombig G, Frank K, Tonn T, Hugo C
Equivalent humoral and cellular immune response but different side effect rates following SARS-CoV-2 vaccination in peritoneal and hemodialysis patients using mRNA vaccines. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2021), DOI Link |
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Stumpf J, Siepmann T, Lindner T, Karger C, Schwöbel J, Anders L, Faulhaber-Walter R, Schewe J, Martin H, Schirutschke H, Barnett K, Hüther J, Müller P, Langer T, Pluntke T, Anding-Rost K, Meistring F, Stehr T, Pietzonka A, Escher K, Cerny S, Rothe H, Pistrosch F, Seidel H, Paliege A, Beige J, Bast I, Steglich A, Gembardt F, Kessel F, Kröger H, Arndt P, Sradnick J, Frank K, Klimova A, Mauer R, Grählert X, Anft M, Blazquez-Navarro A, Westhoff TH, Stervbo U, Tonn T, Babel N, Hugo C
Humoral and cellular immunity to SARS-CoV-2 vaccination in renal transplant versus dialysis patients: A prospective, multicenter observational study using mRNA-1273 or BNT162b2 mRNA vaccine. The Lancet regional health. Europe 9 (2021) 100178, DOI Link |
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Waschke J, Hlawitschka M, Anlas K, Trivedi V, Roeder I, Huisken J, Scherf N
linus: Conveniently explore, share, and present large-scale biological trajectory data in a web browser. PLoS computational biology 17 (2021) e1009503, DOI Link |
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| 2020 | |
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Diebner HH, Kather A, Roeder I, de With K
Mathematical basis for the assessment of antibiotic resistance and administrative counter-strategies. PloS one 15 (2020) e0238692, DOI Link |
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Gottschalk A, Glauche I, Cicconi S, Clark RE, Roeder I
Molecular monitoring during dose reduction predicts recurrence after TKI cessation in CML. Blood 135 (2020) 766-769, DOI Link |
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Hoffmann H, Thiede C, Glauche I, Bornhaeuser M, Roeder I
Differential response to cytotoxic therapy explains treatment dynamics of acute myeloid leukaemia patients: insights from a mathematical modelling approach. Journal of the Royal Society, Interface 17 (2020) 20200091, DOI Link |
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Hoffmann K, Cazemier K, Baldow C, Schuster S, Kheifetz Y, Schirm S, Horn M, Ernst T, Volgmann C, Thiede C, Hochhaus A, Bornhäuser M, Suttorp M, Scholz M, Glauche I, Loeffler M, Roeder I
Integration of mathematical model predictions into routine workflows to support clinical decision making in haematology. BMC medical informatics and decision making 20 (2020) 28, DOI Link |
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Lauber C, Correia N, Trumpp A, Rieger MA, Dolnik A, Bullinger L, Roeder I, Seifert M
Survival differences and associated molecular signatures of DNMT3A-mutant acute myeloid leukemia patients. Scientific reports 10 (2020) 12761, DOI Link |
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Bondarieva A, Raveendran K, Telychko V, Rao HBDP, Ravindranathan R, Zorzompokou C, Finsterbusch F, Dereli I, Papanikos F, Tränkner D, Schleiffer A, Fei JF, Klimova A, Ito M, Kulkarni DS, Roeder I, Hunter N, Tóth A
Proline-rich protein PRR19 functions with cyclin-like CNTD1 to promote meiotic crossing over in mouse. Nature communications 11 (2020) 3101, DOI Link |
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Erdmann K, Salomo K, Klimova A, Heberling U, Lohse-Fischer A, Fuehrer R, Thomas C, Roeder I, Froehner M, Wirth MP, Fuessel S
Urinary MicroRNAs as Potential Markers for Non-Invasive Diagnosis of Bladder Cancer. International journal of molecular sciences 21 (2020), DOI Link |
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Hattab G, Ahlfeld T, Klimova A, Koepp A, Schuerer M, Speidel S
Uniaxial compression testing and Cauchy stress modeling to design anatomical silicone replicas. Scientific reports 10 (2020) 11849, DOI Link |
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Hering S, Klimova A, Edelmann J
German population data for 18 X-STRs: a hexaplex PCR adding two clusters of X-STRs to the Argus X-12 set and expanding the German haplotype databases. International journal of legal medicine (2020), DOI Link |
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Johansson P, Klein-Hitpass L, Budeus B, Kuhn M, Lauber C, Seifert M, Roeder I, Pförtner R, Stuschke M, Dührsen U, Eckstein A, Dürig J, Küppers R
Identifying Genetic Lesions in Ocular Adnexal Extranodal Marginal Zone Lymphomas of the MALT Subtype by Whole Genome, Whole Exome and Targeted Sequencing. Cancers 12 (2020), DOI Link |
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Kloenne M, Niehaus S, Lampe L, Merola A, Reinelt J, Roeder I, Scherf N
Domain-specific cues improve robustness of deep learning-based segmentation of CT volumes. Scientific reports 10 (2020) 10712, DOI Link |
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Machova Polakova K, Zizkova H, Zuna J, Motlova E, Hovorkova L, Gottschalk A, Glauche I, Koblihova J, Pecherkova P, Klamova H, Stastna Markova M, Srbova D, Benesova A, Polivkova V, Jurcek T, Zackova D, Mayer J, Ernst T, Mahon FX, Saussele S, Roeder I, Cross NCP, Hochhaus A
Analysis of chronic myeloid leukaemia during deep molecular response by genomic PCR: a traffic light stratification model with impact on treatment-free remission. Leukemia 34 (2020) 2113-2124, DOI Link |
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Morcos MNF, Zerjatke T, Glauche I, Munz CM, Ge Y, Petzold A, Reinhardt S, Dahl A, Anstee NS, Bogeska R, Milsom MD, Säwén P, Wan H, Bryder D, Roers A, Gerbaulet A
Continuous mitotic activity of primitive hematopoietic stem cells in adult mice. The Journal of experimental medicine 217 (2020), DOI Link |
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Oberbeck S, Schrader A, Warner K, Jungherz D, Crispatzu G, von Jan J, Chmielewski M, Ianevski A, Diebner HH, Mayer P, Kondo Ados A, Wahnschaffe L, Braun T, Müller TA, Wagle P, Bouska A, Neumann T, Pützer S, Varghese L, Pflug N, Thelen M, Makalowski J, Riet N, Göx HJM, Rappl G, Altmüller J, Kotrova M, Persigehl T, Hopfinger G, Hansmann ML, Schlößer H, Stilgenbauer S, Dürig J, Mougiakakos D, von Bergwelt-Baildon M, Roeder I, Hartmann S, Hallek M, Moriggl RH, Brüggemann M, Aittokallio T, Iqbal J, Newrzela S, Abken H, Herling M
Non-canonical effector functions of the T-memory-like T-PLL cell are shaped by cooperative TCL1A and TCR signaling Blood (2020), DOI Link |
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Weitzmann A, Naumann R, Dudeck A, Zerjatke T, Gerbaulet A, Roers A
Mast Cells Occupy Stable Clonal Territories in Adult Steady-State Skin. The Journal of investigative dermatology 140 (2020) 2433-2441.e5, DOI Link |
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| 2019 | |
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Hoffmann H, Thiede C, Glauche I, Kramer M, Röllig C, Ehninger G, Bornhäuser M, Roeder I
The prognostic potential of monitoring disease dynamics in NPM1-positive acute myeloid leukemia Leukemia 33 (2019) 1531-1534, DOI Link |
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de Back W, Zerjatke T, Roeder I
Statistical and Mathematical Modeling of Spatiotemporal Dynamics of Stem Cells Methods in Molecular Biology 2017 (2019) 219-243, DOI Link |
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Fassoni AC, Roeder I, Glauche I
To Cure or Not to Cure: Consequences of Immunological Interactions in CML Treatment Bulletin of Mathematical Biology (2019) 1-51, DOI Link |
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Morales-Navarrete H, Nonaka H, Scholich A, Segovia-Miranda F, de Back W, Meyer K, Bogorad RL, Koteliansky V, Brusch L, Kalaidzidis Y, Jülicher F, Friedrich BM, Zerial M
Liquid-crystal organization of liver tissue eLife 8 (2019) e44860, DOI Link |
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Shah G, Thierbach K, Schmid B, Waschke J, Reade A, Hlawitschka M, Roeder I, Scherf N, Huiken J
Multi-scale imaging and analysis identify pan-embryo cell dynamics of germlayer formation in zebrafish Nature Communications 10 (2019), DOI Link |
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Zakrzewski F, de Back W, Weigert M, Wenke T, Zeugner S, Mantey R, Sperling C, Friedrich K, Roeder I, Aust D, Baretton G, Hönscheid P
Automated detection of the HER2 gene amplification status in Fluorescence in situ hybridization images for the diagnostics of cancer tissues Scientific Reports 9 (2019), DOI Link |
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| 2018 | |
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Diebner HH, Zerjatke T, Griehl M, Roeder I
Metabolism is the tie: The Bertalanffy-type cancer growth model as common denominator of various modelling approaches Biosystems 167 (2018) 1-23, DOI Link |
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Gaspari E, Franke A, Robles-Diaz D, Zweigerdt R, Roeder I, Zerjatke T, Kempf H
Paracrine mechanisms in early differentiation of human pluripotent stem cells: Insights from a mathematical model Stem Cell Research 32 (2018) 1-7, DOI Link |
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Glauche I, Kuhn M, Baldow C, Schulze P, Rothe T, Liebscher H, Roy A, Wang X, Roeder I
Quantitative prediction of long-term molecular response in TKI-treated CML - Lessons from an imatinib versus dasatinib comparison. Scientific Reports 8 (2018) 12330, DOI Link |
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Thierbach K, Bazin P, De Back W, Gavriilidis F, Kirilina E, Jaeger C, Morawski M, Geyer S, Weiskopf N, Scherf N
Combining Deep Learning and Active Contours Opens The Way to Robust, Automated Analysis of Brain Cytoarchitectonics (2018), DOI Link |
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Apweiler R, Beissbarth T, Berthold MR, Blüthgen N, Burmeister Y, Dammann O, Deutsch A, Feuerhake F, Franke A, Hasenauer J, Hoffmann S, Höfer T, Jansen PLM, Kaderali L, Klingmüller U, Koch I, Kohlbacher O, Kuepfer L, Lammert F, Maier D, Pfeifer N, Radde N, Rehm M, Roeder I, Saez-Rodriguez J, Sax U, Schmeck B, Schuppert A, Seilheimer B, Theis FJ, Vera J, Wolkenhauer O
Whither systems medicine? Experimental & Molecular Medicine 50 (2018) e453, DOI Link |
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Fassoni AC, Baldow C, Roeder I, Glauche I
Reduced tyrosine kinase inhibitor dose is predicted to be as effective as standard dose in chronic myeloid leukemia: A simulation study based on phase 3 trial data Haematologica 103 (2018) 1825-1834, DOI Link |
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Sacma M, Pospiech J, Bogeska R, De Back W, Karns R, Sakk V, Soller K, Marka G, Vollmer A, Méndez-Ferrer S, Cabezas-Wallscheid N, Trumpp A, Milsom M, Geiger H, Florian M
Hematopoietic stem cells in perisinusoidal niches are protected from aging Experimental Hematology 64 (2018) 43, DOI Link |
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| 2017 | |
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Baldow C, Salentin S, Schroeder M, Roeder I, Glauche I
MAGPIE: Simplifying access and execution of computational models in the life sciences PLOS Computational Biology 13 (2017) 1-11, DOI Link |
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Diebner HH
Performative Science - Transgressions from Scientific to Artistic Practices and Reverse. In: Stefan C. Müller, Peter J. Plath, Günter Radons, Armin Fuchs (eds.): Complexity and Synergetics Springer, Berlin (2017), ISBN: 978-3-319-64334-2 |
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Proschmann R, Baldow C, Rothe T, Suttorp M, Thiede C, Tauer JT, Müller MC, Hochhaus A, Roeder I, Glauche I
Response dynamics of pediatric patients with chronic myeloid leukemia on imatinib therapy. Haematologica 102 (2017) e39-e42, DOI Link |
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Thielecke L, Aranyossy T, Dahl A, Tiwari R, Roeder I, Geiger H, Fehse B, Glauche I, Cornils K
Limitations and challenges of genetic barcode quantification Scientific Reports 7 (2017), DOI Link |
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Heninger AK, Eugster A, Kuehn D, Buettner F, Kuhn M, Lindner A, Dietz S, Jergens S, Wilhelm C, Beyerlein A, Ziegler AG, Bonifacio E
A divergent population of autoantigen-responsive CD4+ T cells in infants prior to β cell autoimmunity Science Translational Medicine 9 (2017) eaaf8848, DOI Link |
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Herling M, Rengstl B, Scholtysik R, Hartmann S, Küppers R, Hansmann ML, Diebner HH, Roeder I, Abken H, Newrzela S, Kirberg J
Concepts in mature T-cell lymphomas - highlights from an international joint symposium on T-cell immunology and oncology Leukemia & Lymphoma 58 (2017) 788-796, DOI Link |
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Herold S, Kuhn M, von Bonin M, Stange T, Platzbecker U, Radke J, Lange T, Sockel K, Gutsche K, Schetelig J, Röllig C, Schuster C, Roeder I, Dahl A, Mohr B, Serve H, Brandts C, Ehninger G, Bornhäuser M, Thiede C
Donor cell leukemia: evidence for multiple preleukemic clones and parallel long term clonal evolution in donor and recipient Leukemia (2017), DOI Link |
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Hohenstein B, Julius U, Lansberg P, Jaeger B, Mellwig KP, Weiss N, Graehlert X, Roeder I, Ramlow W
Rationale and design of MultiSELECt: A European Multicenter Study on the Effect of Lipoprotein(a) Elimination by lipoprotein apheresis on Cardiovascular outcomes Atherosclerosis Supplements (2017) 180-186, DOI Link |
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MacLean AL, Smith MA, Liepe J, Sim A, Khorshed R, Rashidi NM, Scherf N, Krinner A, Roeder I, Lo Celso C, Stumpf MPH
Single Cell Phenotyping Reveals Heterogeneity Among Hematopoietic Stem Cells Following Infection Stem Cells 35 (2017) 2292–2304, DOI Link |
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Rahmig J, Kuhn M, Neugebauer H, Jüttler E, Reichmann H, Schneider H
Normothermia after decompressive surgery for space-occupying middle cerebral artery infarction: a protocol-based approach BMC Neurology 17 (2017) 205, DOI Link |
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Theil A, Wilhelm C, Kuhn M, Petzold A, Tuve S, Oelschlägel U, Dahl A, Bornhäuser M, Bonifacio E, Eugster A
T cell receptor repertoires after adoptive transfer of expanded allogeneic regulatory T cells. Clinical and experimental immunology 187 (2017) 316-324, DOI Link |
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| 2016 | |
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Glauche I, Scholz M, Löffler M, Roeder I
durch simulation zur optimierten therapie - e:Med-Demonstrator-Projekt HaematoOPT erarbeitet Strategien fuer modellbasierte Optimierung haematologischer Therapien systembiologie.de 11 (2016) 78-82 |
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Herberg M, Glauche I, Zerjatke T, Winzi M, Buchholz F, Roeder I
Dissecting mechanisms of mouse embryonic stem cells heterogeneity through a model-based analysis of transcription factor dynamics. Journal of the Royal Society, Interface 13 (2016) 1-10, DOI Link |
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Kuhn M, Stange T, Herold S, Thiede C, Roeder I
Finding small somatic structural variants in exome sequencing data: a machine learning approach Computational Statistics (2016) 1-14, DOI Link |
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Roeder I, Scholz M, Glauche I
Systemmedizinische Ansätze in Hämatologie und Onkologie Spectrum Onkologie 06 (2016) 50-52 |
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Schoedel KB, Morcos MN, Zerjatke T, Roeder I, Grinenko T, Voehringer D, Göthert JR, Waskow C, Roers A, Gerbaulet A
The bulk of the hematopoietic stem cell population is dispensable for murine steady-state and stress hematopoiesis. Blood (2016) 1-13, DOI Link |
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| 2015 | |
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Diebner HH, Kirberg J, Roeder I
An evolutionary stability perspective on oncogenesis control in mature T-cell populations. Journal of theoretical biology (2015), DOI Link |
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Herberg M, Roeder I
Computational modelling of embryonic stem-cell fate control. Development (Cambridge, England) 142 (2015) 2250-60, DOI Link |
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Herberg M, Zerjatke T, de Back W, Glauche I, Roeder I
Image-based quantification and mathematical modeling of spatial heterogeneity in ESC colonies. Cytometry. Part A : the journal of the International Society for Analytical Cytology (2015), DOI Link |
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Giordano FA, Appelt JU, Link B, Gerdes S, Lehrer C, Scholz S, Paruzynski A, Roeder I, Wenz F, Glimm H, von Kalle C, Grez M, Schmidt M, Laufs S
High-throughput monitoring of integration site clonality in preclinical and clinical gene therapy studies. Molecular therapy. Methods&clinical development 2 (2015) 14061, DOI Link |
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Niederberger T, Failmezger H, Uskat D, Poron D, Glauche I, Scherf N, Roeder I, Schroeder T, Tresch A
Factor graph analysis of live cell imaging data reveals mechanisms of cell fate decisions. Bioinformatics (Oxford, England) (2015), DOI Link |
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| 2014 | |
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Glauche I, Baldow Ch, Fröhlich S, Schulze P, Roy A, Subar M, Wang X, Roeder I
Model-Based Characterization of the Molecular Response Dynamics of Tyrosine Kinase Inhibitor (TKI)-Treated CML Patients a Comparison of Imatinib and Dasatinib First-Line Therapy Blood 124 (2014) 4562 |
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Glauche I, Roeder I
in silico hematology Systembiologie.de 42 (2014) 19 |
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Herberg M, Kalkan T, Glauche I, Smith A, Roeder I
A Model-Based Analysis of Culture-Dependent Phenotypes of mESCs. PloS one 9 (2014) e92496, DOI Link |
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Krinner A, Roeder I
Quantification and modeling of stem cell-niche interaction. Advances in experimental medicine and biology 844 (2014) 11-36, DOI Link |
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Bach E, Zerjatke T, Herklotz M, Scherf N, Niederwieser D, Roeder I, Pompe T, Cross M, Glauche I
Elucidating functional heterogeneity in hematopoietic progenitor cells: a combined experimental and modeling approach. Experimental hematology 42 (2014) 826-37.e1-17, DOI Link |
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Cornils K, Thielecke L, Hüser S, Forgber M, Thomaschewski M, Kleist N, Hussein K, Riecken K, Volz T, Gerdes S, Glauche I, Dahl A, Dandri M, Roeder I, Fehse B
Multiplexing clonality: combining RGB marking and genetic barcoding. Nucleic acids research (2014), DOI Link |
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Rashidi NM, Scott MK, Scherf N, Krinner A, Kalchschmidt JS, Gounaris K, Selkirk ME, Roeder I, Lo Celso C
In vivo time-lapse imaging of mouse bone marrow reveals differential niche engagement by quiescent and naturally activated hematopoietic stem cells. Blood (2014), DOI Link |
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| 2013 | |
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Gerdes S, Newrzela S, Glauche I, von Laer D, Hansmann ML, Roeder I
Mathematical modeling of oncogenesis control in mature T-cell populations. Frontiers in immunology 4 (2013) 380, DOI Link |
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Glauche I, Bystrykh L, Eaves C, Roeder I
Stem cell clonality - Theoretical concepts, experimental techniques, and clinical challenges. Blood cells, molecules&diseases (2013), DOI Link |
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Krinner A, Roeder I, Loeffler M, Scholz M
Merging concepts - coupling an agent-based model of hematopoietic stem cells with an ODE model of granulopoiesis. BMC systems biology 7 (2013) 117, DOI Link |
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Scherf N, Ludborzs C, Thierbach K, Glauche I, Roeder I
A Fluid Registration Approach to Cell Tracking Current Medical Imaging Reviews 9 (2013) 102-12 |
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Cornils K, Bartholomae CC, Thielecke L, Lange C, Arens A, Glauche I, Mock U, Riecken K, Gerdes S, von Kalle C, Schmidt M, Roeder I, Fehse B
Comparative clonal analysis of reconstitution kinetics after transplantation of hematopoietic stem cells gene marked with a lentiviral SIN or gamma-retroviral LTR vector. Experimental hematology 41 (2013) 28-38.e3, DOI Link |
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Horn M, Glauche I, Müller MC, Hehlmann R, Hochhaus A, Loeffler M, Roeder I
Model-based decision rules reduce the risk of molecular relapse after cessation of tyrosine kinase inhibitor therapy in chronic myeloid leukemia. Blood 121 (2013) 378-84, DOI Link |
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Kustikova OS, Schwarzer A, Stahlhut M, Brugman MH, Neumann T, Yang M, Li Z, Schambach A, Heinz N, Gerdes S, Roeder I, Ha TC, Steinemann D, Schlegelberger B, Baum C
Activation of Evi1 inhibits cell cycle progression and differentiation of hematopoietic progenitor cells. Leukemia 27 (2013) 1127-38, DOI Link |
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Schmid B, Shah G, Scherf N, Weber M, Thierbach K, Campos CP, Roeder I, Aanstad P, Huisken J
High-speed panoramic light-sheet microscopy reveals global endodermal cell dynamics. Nature communications 4 (2013) 2207, DOI Link |
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